
|
|
HEPATITIS B
by Dr. Rajesh Shah
|
|
|
|
|
|
Definition:
Hepatitis B is a viral infection caused by the Hepatitis B
virus (HBV). This virus is capable of causing life-long
infection, liver cirrhosis (scaring), liver failure, liver
cancer and death. |
|
|
|
 |
|
|
|
Cause: |
|
As mentioned above the cause of
Hepatitis B is the virus- HBV. The virus spreads when
blood from an infected person enters the body of a
non-infected person. This virus enters the blood stream
and reaches the liver where it reproduces and releases
large numbers of new viruses into the bloodstream. HBV can
survive outside the body for at least 7 days and can still
be capable of causing infection.
|
|
HBV is mainly found in the blood of infected individuals.
Saliva, semen, vaginal secretions and breast milk also
contain the virus but in lower concentrations as compared
to the blood. Feces, nasal secretions, sputum, sweat,
tears, urine and vomit have not been implicated in the
spread of Hepatitis B. Unless they are visibly
contaminated with blood, the risk of contracting hepatitis
B from these fluids is practically nonexistent. Hepatitis
B is not transmitted by casual contact, hugging, by
sharing eating utensils, through food or water, etc.
|
|
After a person has been exposed to the HBV, the blood test
(HBsAg) will become positive on an average within 4 weeks
(range 1- 9 weeks). Usually within 15 weeks of onset of
the symptoms, this test becomes negative in most
individuals (except those who have developed chronic
infection).
|
|
|
|
|
|
Risk factors
for developing Hepatitis B:
|
- Sexual contact with an infected individual
- Sexual contact with multiple partners
- Male homosexual contact
- Intravenous drug abuse (due to sharing of infected
needles)
- Health care workers (due to close contact with
infected individuals)
- Occupational blood exposure
- Sharing toothbrushes, razors, etc
- From an infected mother to new-born infant
- Chronic renal failure patients on Dialysis
- Tattooing, piercing of skin (ears, lips, navel, etc)
- Dental procedure
- Medical procedures (including transfusion of blood
or blood products)
- Staying with a chronic Hepatitis B patient
- Travelling to countries which have a high prevalence
of Hepatitis B
|
|
It must be noted that people of
any age, sex, race or nationality can be infected by this
virus. |
|
|
|
 |
|
|
|
Symptoms:
Sometimes a person with HBV infection may not have any
symptoms at all. In patients who do develop symptoms, they
occur on an average of about 12 weeks (range 9-21 weeks)
after exposure to hepatitis B virus. About 70% of the
patients develop symptoms of Hepatitis B. The symptoms
include: |
- Jaundice: Yellowness of skin and/or sclera (white
portion of the eyes)
- Loss of appetite
- Abdominal discomfort
- Nausea with or without vomiting
- Dark yellow urine
- Clay coloured stools
- Lethargy, fatigue
- Bodyache, joint pain, etc
|
|
|
|
About Chronic
Hepatitis B infection:
Chronic Hepatitis B means that the body did not get rid of
the virus when the patient was first infected with HBV
thus leading to long-term HBV infection. The younger the
age group at the time of first infection with this virus,
the higher is the chance of developing chronic HBV
infection. Thus almost 90% of infected infants, about 30%
of infected children between 1-5 years of age and only 2-
6% of infected people above 5 years of age will develop
chronic infection.
Carriers of Hepatitis B are those individuals who are
capable of transmitting the virus to other individuals.
Majority of hepatitis B carriers are asymptomatic
(displaying no symptoms) whereas only 30% of them show
symptoms of the disease.
|
|
Diagnosis:
Following are some of the common tests used to diagnose
Hepatitis B infection:
Hepatitis B Surface Antigen (HBsAg): It can be
detected in high levels in serum during acute or chronic
hepatitis. The presence of HBsAg indicates that the person
is infectious.
Hepatitis B Surface Antibody (anti-HBs): The body
normally produces antibodies to HBsAg as a part of the
normal immune response to infection. The presence of anti-HBs
is generally interpreted as indicating recovery and
immunity from HBV infection. Anti-HBs also develops in a
person who has been successfully vaccinated against
hepatitis B.
Hepatitis B e Antigen (HBeAg): This is found in the
serum during acute and chronic hepatitis B. The presence
of Hepatitis B envelope antigen (HBeAg) indicates that the
virus is replicating and the infected individual has high
levels of HBV.
Hepatitis B e Antibody (anti-HBe): This is produced
by the immune system temporarily during acute HBV
infection.
Hepatitis B core antibody (anti-HBc): This is an
antibody to the hepatitis B core antigen. The core antigen
is found on virus particles but disappears early in the
course of infection. This antibody is produced during and
after an acute HBV infection and is usually found in
chronic HBV carriers as well as those who have cleared the
virus, and usually persists for life. |
|
|
|
..............Hepatitis B tests interpretation |
|
TEST |
RESULT |
INTERPRETATION |
|
HBsAg
anti-HBc
anti-HBs
|
Negative
Negative
Negative |
Susceptible to Hepatitis B infection |
|
HBsAg
anti-HBc
anti-HBs
|
Negative
Positive
Positive |
Immune due to natural infection |
|
HBsAg
anti-HBc
anti-HBs
|
Negative
Negative
Positive
|
Immune due to Hepatitis B vaccination |
|
HBsAg
anti-HBc
IgM anti-HBc
anti-HBs
|
Positive
Positive
Positive
Negative
|
Acutely infected |
|
HBsAg
anti-HBc
IgM anti-HBc
anti-HBs
|
Positive
Positive
Negative
Negative
|
Chronically infected |
|
HBsAg
anti-HBc
anti-HBs
|
Negative
Positive
Negative
|
* 4 Interpretations possible |
|
* 4 interpretations:
-
Patient might be recovering from acute HBV infection
-
Patient might be immune and the test may not
be sensitive enough to detect very low level of
anti-HBs in serum
-
Patient might be susceptible and may be
having a false positive anti-HBc
-
Patient may be actually chronically infected
and may be having undetectable levels of HBsAg in
the serum
|
|
|
|
|
Complications of Hepatitis B:
These include the following: |
- Chronic hepatitis
- Cirrhosis
- Liver failure
- Hepatocellular carcinoma
|
|
Homeopathic
Treatment: Homoeopathy is known to work to the
immunological level, and has proven its efficacy in the
treatment of a wide range of viral infections. With
homoeopathic medicines, the cases of Hepatitis B are
better controlled, the process of cirrhosis is well kept
under check and symptomatic relief is also obtained very
well. Homoeopathic treatment can also help in delaying the
complications of Hepatitis B (such as cirrhosis and liver
cancer) as far as possible. It may also be noted that the
treatment for chronic Hepatitis B has to be planned for a
longer duration of time. The best part of homeopathic
treatment is that the disease is kept under control and
general health improved without any kind of side-effects
whatsoever.
|
|
|
|
|
Click here to view Case Study of
Hepatitis B
Click here for more Articles |